The team analyzed 302,706 reports, including 17,853 mentioning obesity as an indication, 283,238 mentioning type 2 diabetes, and 1,615 mentioning both conditions
(2025a)
More participants in the semaglutide group than in the placebo group achieved weight reductions of 5% or more (86% of participants vs 32%), 10% or more (69% vs 12%) and 15% or more (51% vs 5%) at week 68
Generally, patients may lose about four to ten pounds per month when starting Ozempic treatment
One of the reasons is that todays self-injectors, especially single-use pre-filled syringes, have fine needles that cause less pain compared to vaccination or blood draw needles, according to Lake
These include: Nausea (very common, affecting more than 1 in 10 people) Vomiting and diarrhoea (common) Abdominal pain and decreased appetite (common) Constipation and indigestion (common) These symptoms often improve as the body adjusts to the medication