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NICE advises continuing treatment only if there is a clinically meaningful HbA1c reduction (for example 11 mmol/mol [1%]) and weight loss of at least 3% of initial body weight

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NICE guideline NG109

Tryptic digests of amaranth produced hydrolysates with dose-dependent increase in inhibitory activity and which had IC 50 values between 12 and 20 mg/ml ( Reference Velarde-Salcedo, Barrera-Pacheco and Lara-Gonzlez 56 )

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