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Further investigation showed that CPs first reduce the level of skin oxidation, inhibit the expression of the key transcription factor AP-1 (c-Jun and c-Fos), then activate the TGF-/Smad signaling pathway to promote collagen synthesis, inhibit the expression of MMP-1/3 to inhibit collagen degradation, and inhibit skin inflammation to alleviate skin aging in mice

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Endothelial dysfunction, which refers to an imbalance between various factors involved in relaxation and contraction, coagulation and anticoagulation, as well as inflammation and anti-inflammation, may play a substantial role in the pathogenesis of atherosclerosis and cardiovascular disease (94)

Because they serve different functions, many people find that they work best when used together as part of a comprehensive routine

Glutathione S transferase polymorphisms influence on iron overload in -thalassemia patients