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In the U.K., obesity costs to the National Health Service are projected near 12 billion (US $16.1 billion) in 2025, with total societal costs exceeding 73 billion (US $98.1 billion) [3,4]

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Will a plateau be reached

For multi-arm studies or extended longitudinal work where between-condition consistency is a controlled variable, drawing from a single sealed 40mg supply is the cleaner experimental design

Some patients notice changes in appetite and early weight loss within the first few weeks, while others require dose titration over several months to achieve meaningful effects

not a product safety finding, but a signal about oversight culture