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Limited Direct Evidence No published clinical trial has evaluated glutathione supplementation as a standalone or adjunctive treatment for hair loss

Mitochondria as multifaceted regulators of ferroptosis

At low concentrations (0.01 nM), MMP1 and MMP2 gene expression increases, facilitating removal of damaged ECM proteins

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However, it should be noted that GSH at high concentrations (e.g., 30 mM) induces morphological changes in HFF-1 cells (Supplementary Figure S1E)