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A recent study demonstrated the ability of a dendrimer-conjugated NAC (D-NAC) to specifically target glial and astrocyte cells, indicating potential to alter GSH levels in specific cell populations without altering levels throughout the CNS (Nance et al., 2017

In practice, researchers often study one from each group side by side a signalling peptide to change how a cell behaves, and a cofactor to support the machinery that behaviour depends on

A researcher on 12mg would move to 8mg for four weeks, then 4mg for four weeks, then 1mg for four weeks before discontinuing entirely

But there is a whole other group that is non-excreters

Metab Brain Dis 29:1936

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