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Handling is restricted to trained and properly licensed professionals

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Retrieved February 22, 2016, from 2 Geppetti P, et al

A 2015 meta-analysis published in Phytomedicine found berberine supplementation associated with modest reductions in BMI, fasting glucose, and triglycerides compared to placebo

WADA Prohibition The World Anti-Doping Agency classifies both peptides as prohibited substances: Both listed under Section S0 (Non-Approved Substances) Prohibited at all times (in and out of competition) No Therapeutic Use Exemptions (TUEs) available for either peptide Detection methods under development for anti-doping testing TB-500 and thymosin beta-4 explicitly banned since 2011 WADAs position reflects that neither peptide has regulatory approval from any health authority worldwide

A study by Korkushko and colleagues found that Epithalon significantly improved melatonin synthesis and normalized circadian rhythm of cortisol secretion in elderly patients, leading to better sleep quality and overall well-being