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The model is based on data from both in vitro measurements on isolated adipocytes, and in vivo microdialysis measurements, in both cases from non-diabetic individuals

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using fat cells collected from murine models exposed to a truncated version of AOD9604 that contains the (177191) amino acids

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In a pilot study during 1 month of four patients with Crohns disease the mean serum cobalamin concentration increased significantly after weekly administration of 1500 g of the same formulation