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The field is currently moving toward unimolecular polypharmacology (Jimenez-Solem et al., 2010)

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Instead of producing darker eumelanin, cells exposed to high glutathione tend to produce more of the lighter, reddish pheomelanin

Secondly, the high cost of tirzepatide treatment (approximately tens of thousands of dollars per year) may limit its widespread use in economically constrained regions (such as mainland China)