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Because hormones are affected by metabolism and body fat, some individuals notice changes in joint comfort during rapid weight loss

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Patients should contact their GP or diabetes specialist nurse if: Gastrointestinal side effects persist beyond the first few weeks or significantly impact quality of life They experience signs of dehydration due to vomiting or diarrhoea They have recurrent hypoglycaemia They develop visual changes or symptoms of gallbladder disease (e.g., right upper abdominal pain) Any new or concerning symptoms develop Regular monitoring of HbA1c, renal function, and body weight is recommended during treatment with Rybelsus

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The FDA also warns that non-FDA-approved drugs may be dangerous and contain unknown ingredients

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