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Early investigations indicated that incubating dermal fibroblasts with nanomolar concentrations of GHK-Cu may have increased the synthesis of collagen, elastin, glycosaminoglycans (GAGs), and small proteoglycans such as decorin

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Metformin induces microRNA-34a to downregulate the Sirt1/Pgc-1/Nrf2 pathway, leading to increased susceptibility of wild-type p53 cancer cells to oxidative stress and therapeutic agents