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Reduced serum free carnitine as well as reduced levels of 3-keto-VPA, the main metabolite of -oxidation of VPA, was first reported in 1982 by Bohles and coworkers [53] in a 3-year-old girl who developed acute liver disease with typical features of Reye's syndrome after treatment with VPA for 6 months
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The time to steady state for LCPT based on t 1/2eff is shown in Figure 2
administration of d-allulose (1 g kg 1 ) at 60 min significantly lowered basal blood glucose level at 0 min, and suppressed rises in blood glucose level at 15120 min and its AUC for 0120 min period in ipGTT (Fig
L-carnitine and acetyl-L-carnitine enhance mitochondrial activity and energy metabolism by restoring the NAD(H)/NADP(H) ratio, thereby mitigating ROS-induced damage
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