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While these medications are highly effective, they often lead to rapid weight loss, which can have side effects on the body, particularly the face

Headache 2017;57:1303-10

Long-term safety data suggest that gastrointestinal side effects, including diarrhoea, tend to decrease in frequency and severity after the first three months of therapy

Anti-cancer potential of citrus juices and their extracts: A systematic review of both preclinical and clinical studies

It often extends into the deep dermis and may involve the subcutis

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