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General information about the safe and effective use of NASCOBAL

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Metabolic pathway requiring 5-deoxyadenosylcobalamin The figure illustrates the metabolic pathway for the vitamin B 12 -dependent enzyme L-methylmalonyl-CoA mutase, which converts L-methylmalonyl-CoA into succinyl-CoA for entry into the citric acid cycle

In some cases, once a patient turns 18, transitioning from the adolescent-approved injectable to the daily oral pill may be a viable strategy

Vitamin B12 is believed to be safe when used orally in amounts that do not exceed the recommended dietary allowance (RDA)