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2.3 Role of taste receptors in the gastrointestinal hormone secretion Although, we commonly associate TRCs and TASR only to the oral cavity, they are also localized in extra-oral tissues, including the gastrointestinal tract, where they participate in energy homeostasis by modulating enteroendocrine hormone release (GLP-1, GIP, CCK, PYY) and nutrient sensing, thereby influencing gastric emptying and metabolic adjustments (e.g., glycemia) (15, 59, 60)

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Stanley S, Domingos AI, Kelly L, Garfield A, Damanpour S, Heisler L, et al

Neal B, Perkovic V, Mahaffey KW, et al

This lasting effect happens because GLP-1/GIPs work with the body's natural metabolism, helping to reset appetite signals and encourage healthier eating habits over time