PMCID: PMC11386968 Paschou IA, Sali E, Paschou SA, Psaltopoulou T, Nicolaidou E, Stratigos AJ
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As the advantages of exendin-4 in vivo were detectable acutely, in a dose-dependent manner, it is likely that they are partly attributable to agonist potency differences rather than the post-endocytic trafficking phenotypes
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Master transcriptional regulators of mitochondrial biogenesis Peroxisome proliferator-activated receptor (PPAR)- coactivator-1 (PGC-1) It is the most important transcriptional cascade regulator in mitochondrial biogenesis, facilitating the transcription of mitochondrial proteins and the replication of mtDNA, which are key steps in mitochondrial biogenesis mentioned above [13]
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