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Marked improvements in lipid profile and blood pressure were also observed compared to placebo [81]
For example, the treatment with acetyl-l-carnitine induced haeme oxygenase enzyme in rat astrocytes in a dose- and time-dependent fashion, heat shock protein 60 upregulation, and increased expression of the nuclear factor erythroid 2-related factor 2 transcription factor, a master regulator of antioxidant proteins [18]
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[73], IL-8 and monocyte chemoattractant protein-1 (MCP-1) levels were shown to be significantly higher in CSF from ALS patients versus control (non-inflammatory neurological disease) patients
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