These compounds work by signaling the body to increase its own natural growth hormone production, which plays a role in muscle growth, recovery, and body composition
If emotional eating is your primary pattern, GLP-1 is a partial tool
If lower doses are working or if there are side effects it makes sense to stay longer at the lower doses however as you can see in the study above, the 25 mg dose is where the full treatment effect was noted
The UACR reductions were dose-dependent, larger at higher doses, and sustained through 72 weeks of treatment without any detrimental effect on estimated glomerular filtration rate
Those with significant medical co-morbidities, prior CSF diversion procedures, neurovascular stenting or optic nerve sheath fenestration, those currently using GLP-1 receptor agonists, dipeptidyl peptidase-4 (DPP-4) inhibitors or taking drugs that could reduce ICP were excluded
Additionally, patients exploring alternative GLP-1 options may compare outcomes with physician-led Tirzepatide programs when clinically appropriate