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(2026): Glucagon-like peptide 1-based therapies for the treatment of type 2 diabetes mellitus

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The recommended dose is two capsules daily, one in the morning and one in the evening

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These model values correspond well to the values in the literature

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M1-dominant macrophages overproduce TNF- and IL-6, directly blocking insulin receptor signalling in metabolically active tissues [4]

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High-intensity interval training (HIIT) can improve insulin sensitivity

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