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Advances in Peptide Research, 22 (3), 121-134

59 These findings suggest that vesicle-mediated signaling may either amplify or restrain ferroptosis depending on cargo composition and uptake efficiency, highlighting extracellular vesicles as bidirectional regulators of ferroptotic susceptibility rather than unidirectional death signals

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During the oxidation of hydrogen sulfide, SQOR generates elemental sulfur (S 0 ), which can react with intracellular thiols, such as GSH, to form GSH persulfide (GSSH) or thiosulfate 97

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36 , 16791695.e1676 (2024)