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Inflammation and metabolic disorders

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SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation

This is the first published trial to study the impact of a GLP-1 RA in a population with significant CKD, and it supports the renal benefits that had previously been suggested in some of the GLP-1 RA cardiovascular outcome trials