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Zhao H, Li M, Zhang X, Li L, Yan Y, Wang B
Finally, we showed that pharmacological inhibition of the thioredoxin system by the chemotherapeutic drug arsenic trioxide (ATO) enhanced MTX cytotoxicity in vivo against one out of four primary human ALL cells, suggesting a novel therapeutic rationale to be further explored against ALL
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Supports Antioxidant Defense Glutathione plays a central role in protecting cells from oxidative stress.*