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To annotate the non-neuronal cell populations, clustering was run at a resolution of 0.1 and 1, and labels were transferred from a published AP-centric DVC atlas 41
Our analysis, based on several FDA trials and observed GLP-1 effects to date, suggests significant reductions in: Musculoskeletal interventions Sleep apnea severity Cardiometabolic complications Need for CPAP equipment Progression to joint replacement surgeries We expect these effects to accelerate in 2026
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Over time, the right ventricle enlarges and eventually fails
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