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In rodent studies, semaglutide caused dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures

As this was a retrospective study, detailed information regarding potential initial dose adjustments or titration strategies was not consistently available in the medical records

Higher doses are more effective for skin brightening because melanin inhibition is dose-dependent

To be fair, their thinking has merit

Vitamin B12 plays a key role in converting food into energy, forming DNA, and producing nerves

doi: 10.1016/j.regpep.2010.04.009 49 SammsRJChristeMECollinsKAPirroVDrozBAHollandAKet al