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Oral: no viable (degradacin GI)
Furthermore, empirical proof on their long-term cost-effectiveness, especially in mitigating problems associated with obesity and diabetes, might substantiate their economic worth (Hamed et al
NICE guidance recommends a holistic approach to managing type 2 diabetes, which includes optimising glycaemic control, managing cardiovascular risk factors, and supporting patients to make sustainable lifestyle changes
Stimulants stress the cardiovascular system, particularly problematic when combined with androgens
Premenopausal women with functioning ovaries typically have enough estrogen production to compensate for the loss from adipose tissue, though exceptions exist, especially with very rapid or very significant weight loss
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