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Timing Optional Monitoring guidance is pathway-based because compound-specific clinical monitoring standards for AOD-9604 are not established

Does body weight affect AOD-9604 dosing

Extended treatment continued to limit body weight gain and white adipose tissue mass, lowered total plasma cholesterol, and showed measurable accumulation in adipose tissue consistent with the compounds lipophilic profile

This is the run-in period where NNMT inhibition is being established

Intramuscular (IM) : Common sites include the upper arm (deltoid muscle), thigh (vastus lateralis), or buttocks (gluteus medius)

Mitochondrial & Energy Support NAD precursors (NR/NMN) Complements NAD preservation (no internal link in map)