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For example, microsatellite stable colorectal cancer (MSS CRC) cells accumulate distal cholesterol precursors (DCPs) due to asynchronous cholesterol biosynthesis, polarizing T cells toward a pro-tumorigenic Th17 phenotype and promoting immune suppression
Eisner (Fellow of the American College of Emergency Physicians), Mikael Ryden (Karolinska Institutet), Heiichiro Udono (Okayama University), Naoto Hirano (University of Toronto), and Masahiko Endo (Hirosaki University) for their critical reading of the manuscript
Primary Handling Editor: Nick Bernard, in collaboration with the Nature Immunology team
The Wall-Side Addition: This is crucial
Note that if non-Medicare patients are treated with a portion of the same vial, it would be expected that those non-Medicare patients be billed for their pro rata share of wastage
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