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However, ethanol feeding induced CYP2E1 expression in WT mice to levels comparable to those observed in KO mice (Fig

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Could there be unwanted effects, like cancer or tumor growth

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Further the interactions of the non-covalently bound coenzyme ThDP-magnesium with the protein component are at five critical sites containing arginines (Arg 101, Arg 318, Arg 395, Arg 401 and Arg 474and Asp155) [101] contribute to dimer formation, stability or catalytic activity [102, 96]

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