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However, unlike a recent report where constitutive loss of IGF-1Rs specifically in the myocardium of male mice prevented age-related alterations to the heart 30 , late-life mAb treatment failed to preserve or restore these same parameters in male animals (Fig

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This is a significant convenience advantage over survodutide, which would likely require manual injection from vials initially (assuming it follows the typical path of newer injectables)

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