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In its role as an electron donor, GSH is instrumental in reducing disulfide bonds in cytoplasmic proteins to cysteines

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This oxidative stress plays a central role in disease progression from simple steatosis to more serious conditions such as non-alcoholic steatohepatitis (NASH), fibrosis, and potentially cirrhosis

Clinicians can frame these outcomes as supportive and adjunctive rather than curative, emphasizing that GHK-Cu enhances the results of a comprehensive regimen rather than replacing cornerstone interventions such as sun protection, neuromodulators, or energy-based devices

The dual role of NRF2 in colorectal cancer: targeting NRF2 as a potential therapeutic approach