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doi: Luz, Y., Calvi, I.P., Marques, I.R., Cruz, S.A., Messias, E., Emanuel, P., Azevedo, H., Cardoso, R., Moura, F.A

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The results were impressive, with participants on the 12 mg dose losing 28.3% of their body weight on average, a figure that surpasses many current weight loss medications

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However, long-term safety in humans requires further research

While anatomic narrowing of the upper airway is a critical factor, most patients also exhibit abnormalities in nonanatomic traits, such as pharyngeal muscle responsiveness, central neurohormonal control of breathing, and an awakening response [10]