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In contrast to the incretin hormones, where cleavage by DPP-4 results in a loss of their insulinotropic activity, cleavage of PYY results in altered receptor selectivity
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Congratulations Lindsay Zasadzinski, MPH, Tamkeen Khan, PhD, Greg Wozniak, Jianing Yang, Stavros Tsipas & Susan Sutherland, MS, PhD To view or add a comment, sign in 14,552 followers
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But theres at least one culprit which may explain both failure points
This distinguishes it from other peptides like CJC-1295 and Ipamorelin, which stimulate natural growth hormone release
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