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1,2 No increase in serious heart events (heart attack, stroke) has been reported, but a dedicated cardiovascular outcomes trial is still pending

In addition to its use for psychological complaints, St

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In fact, we previously reported that systemic MOTS-c treatment reversed diet-induced obesity and diet- and age-dependent insulin resistance in mice 15

Moreover, there is a need for additional studies that identify patients or sub-types of patients with various addictions who might benefit from treatment with such medications: for instance, the possibility that polymorphisms in the GLP-1R genes influence the treatment outcome of GLP-1R agonists on alcohol drinking in patients with AUD