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We demonstrated that at 0.4% hematocrit, there is an exacerbated increase in PS exposure and hemolysis induced by BAY 43-9006, when compared to 4% hematocrit ( Figure 1 )

Although it may take longer to achieve desired results, it significantly reduces the risk of adverse effects

This 30mg vial provides an elevated concentration for extended preclinical trials and dose-response studies

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10.1016/j.nut.2017.08.001 3

Petrie BACKGROUND Heart failure with preserved ejection fraction is increasing in prevalence and is associated with a high symptom burden and functional impairment, especially in persons with obesity