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Add The New York Post on Google From sagging jowls and sulfurous burps to deflated breasts and surprise pregnancies, the side effects of GLP-1 weight-loss drugs have ranged from subtle to strange

Despite the observational nature of this pharmacovigilance study and the inherent limitations of the FAERS database, our preliminary findings in this work could provide a better basis for understanding the potential psychiatric AEs that may occur with GLP-1 RA treatment, assisting clinicians to focus on these AEs and provide early intervention for optimal risk management

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While this study, which has not been published yet in a peer-reviewed journal, did not involve people with diabetes, it is likely that semaglutide would produce similar outcomes among individuals with diabetes, said Routhenstein

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Later work examined NNMT inhibition combined with dietary changes in obese mice, reporting reductions in body weight, fat mass, and hepatic fat, alongside shifts in gut bacterial populations