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However, not all individuals produce UroA efficiently owing to variations in gut microbiome composition, which has led to the development of direct supplementation strategies to achieve consistent levels across different populations (Reference Singh, DAmico and Andreux11)

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It is a compound that occurs naturally in food - the ingredient can be found in products such as whole grain cereals, yeast, eggs or vegetables such as broccoli, peas and tomatoes

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Knockdown of MALAT1 attenuates high-glucose-induced angiogenesis and inflammation via endoplasmic reticulum stress in human retinal vascular endothelial cells