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demonstrated greater survival, preserved LV function, decreased myocyte apoptosis and reduced caspase-3 activation on chronic GLP-1 infusion in spontaneously hypertensive, heart failure prone rats [74]
Why It Matters: Competes strongly in the oral GLP-1 race, alongside semaglutide (oral 2.0), Lillys orforglipron, and emerging small-molecule programs
The Game Changer: Reconstitution and Its Impact on Stability Everything changes the moment you add liquid
If vomiting or diarrhea occurs, switch to electrolyte drinks to replace the vital minerals your body is actively losing
The GLP-1 hormone naturally decreases after meals, but Wegovy maintains elevated levels for extended periods
While obesity is a chronic, relapsing condition, there remains some uncertainty around whether patients need to continue to take the drugs for life
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