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Potential Synergies Complementary Actions: Since GLP-1 focuses on metabolism while GLP-2 targets gut health, they dont compete for the same receptors or mechanisms
For Hashimoto's patients, this discontinuation requires careful planning because: Thyroid hormone requirements increase significantly during pregnancy (typically 25-50% higher) Weight regain after GLP-1 discontinuation will change levothyroxine requirements again Optimal thyroid function before conception is critical for fetal brain development If you discover you are pregnant while on a GLP-1 medication , stop the medication immediately and contact your healthcare provider for urgent thyroid function testing and levothyroxine dose adjustment
A consistent theme across conference discussions at ASN 2025 reinforced that kidney care is becoming more multidisciplinary, and GLP-1 therapies are helping to quietly accelerate that transition
W., Wang, Y
Accepted: March 20, 2021
In humans, the biosynthesis of 13-HODE requires LOX enzymes, glutathione peroxidases 39,61,62,63 , or non-enzymatic processes 39,64
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