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S-Acetyl glutathione S-acetyl glutathione is a modified form where an acetyl group is attached to the sulfur atom of the cysteine residue

Measurement of mitochondrial respiratory functions Freshly isolated mitochondria (5 g protein) from GSH depleted with or without NAC treated HepG2 cells were suspended in 1.0 ml of 20 mM KPi buffer, pH 7.4, in the presence of the detergent, lauryl maltoside (0.2%)

Science 332 , 14331435 (2011)

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Unfortunately, glutathione levels decline with age, most specifically due to poor nutrition, stress, and to toxins from the environment