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This review synthesizes current evidence on the definition, prognostic assessment, and pathophysiology of SAH, critically appraises existing and emerging therapies, and highlights the need for combination strategies, improved patient stratification, and personalized treatment approaches

An increase in gastrin level is a feedback reflex to the hypoacidity (higher gastric pH) induced by the potent acid suppression of PPI

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doi: 10.1016/j.jaad.2022.04.025 169 HarrellMIIritaniBMRuddellA

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In addition, it provides patients with a clear understanding of their treatment plan, which can improve compliance and overall satisfaction