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To elucidate the effect of GCLC and glutathione loss on brain homeostasis, we biochemically and histochemically analyzed brain pathologies in neuronal GCLC-conditional knockout (GCLC floxed X CaMKII-Cre

For each experiment, two to three rats were decapitated

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Researchers believe metabolic dysfunction, inflammation, and insulin resistance may contribute to neurodegeneration

We next compared ICV versus intraperitoneal (IP) administration of mGIPR-Ab in diet-induced obese (DIO) mice