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Jacobs Patrick L
The fibrotic effects of TMAO on human renal fibroblasts is mediated by NLRP3, caspase-1 and the PERK/Akt/mTOR pathway
A diverse, healthy microbiome = more GLP-1-stimulating SCFAs
Boosted immunity
Two groups of pathways were detected in all four clusters: the pathways related to skeletal muscle development and differentiation, and the pathways that regulate cell migration, including ameboidal-type migration common for myoblasts activated to fuse with pseudopodial sprouts
These transgenerational effects operate primarily through epigenetic modifications, germline transmission of molecular alterations, and persistent fertility impairments that challenge traditional concepts of toxicological risk assessment (84)
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