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The scale may not move dramatically even as patients see visible changes in the mirror and clothing fit

Erythrocytes affect hemostasis and thrombosis by altering blood viscosity, blood flow dynamics, secreting RBC-derived microvesicles, interactions with platelets or endothelial cells, fibrinogen-induced RBC aggregation, activation of blood coagulation factors, direct modulation of thrombin and fibrin formation, or formation of polyhedral-like erythrocytes in thrombi [47,48,49]

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Subsequently, 800 L of upper aqueous layer was centrifugally filtered through a Millipore 5-kDa cutoff filter at 9100 g and 4 C for 120 min to remove proteins