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9, 2025), available at: [3] FDA, FDAs Concerns with Unapproved GLP-1 Drugs Used for Weight Loss , (last visited: Sep
Acknowledgements The authors thank Michael Bonar, Creative Director at the Leicester Diabetes Centre, for the original figure concept
doi: 10.1002/hep.23569 11
In the late 2000s, still haunted by the fallout from drugs like rosiglitazone (brand name Avandia), linked to increased heart attack risk, the FDA laid down a blunt new rule: every new diabetes drug must prove it wont harm the heart before it ever sees pharmacy shelves
The wells were washed (350 L/well) six times with Working Strength Wash Buffer and incubated for 30 min with TMB substrate (100 L/well), before Stop Solution (100 L/well) was added