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doi:10.12991/201014455 Pickart L, Vasquez-Soltero JM, Margolina A
Smits RM, et al
De Flora S, Grassi C, Carati L
Buy Now A hydrating cream that helps treat melasma and hyperpigmentation to lighten and fade dark spots on the face
Popular over-the-counter cosmeceutical ingredients and their clinical efficacy, 13
Unopened lyophilized powder storage Lyophilized (freeze-dried) GHK-Cu powder: Most stable form Water removed = minimal degradation Longest shelf life achievable How vendors ship Typical: 50mg or 100mg vials Storage conditions and shelf life: Why freezer optimal: Lowest degradation rate Extends shelf life 2-4x Minimal oxidation Best for long-term storage Industry standard Refrigerator acceptable: Convenient daily access Still good shelf life (12-18 months) Fine for near-term use ( 4 months Any foul odor (rare but indicator) Testing potency (impossible at home): No home test for GHK-Cu potency Must trust storage conditions Vendor testing (if available) Err on side of caution When uncertain, discard and replace Reconstituted GHK-Cu solution shelf life After adding bacteriostatic water
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