To finish up the side effects, the discontinuation rate excluding the weight loss stoppages appears at least a bit more reasonable as in most obesity trials the stop rate is usually 5-8% which only leaves the 12mg as an outlier still, but like I said earlier, we need side effects over time and just more data in general to see whats going on with that dose
If GLP-1s do quell food noise and therefore cravings, that could pose a threat. In fact, The Hershey Company has already reported a mild year-on-year impact as a result of GLP-1 drugs
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