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The oxygen free radicals oxidize the lipid because the granulocytes and macrophages produce an excess amount of O 2 , H 2 O 2 during the phagocytosis

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7.4 Bloodbrain barrier breakdown and brain inflammation The BBB, much like the intestinal barrier, becomes more permeable under inflammatory stress, allowing inflammatory mediators and microbial by-products to reach the brain

Platelet-rich plasma (PRP) in osteoarthritis (OA) knee: correct dose critical for long term clinical efficacy. Scientific reports 11.1 (2021): 3971

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