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That could be the case if your body isn't producing enough glutathione to protect itself from the free radicals that lead to oxidative stress

Glutathione can function on its own, but Vitamin C significantly enhances its absorption and helps regenerate it in the body

A Look at the Evidence Saffron has been studied for a fairly wide range of uses: mood and depression, sleep, PMS, menopause symptoms, eye health, and appetite

Cancer Chemother Pharmacol 71:555564