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Neutrophils that undergo ferroptosis may die and emit damage-associated molecular patterns (DAMPs), which intensifies the inflammatory response ( 3.4.3 T cells The inflammatory response and tissue damage seen in ARDS are largely caused by T cells, which are essential elements of the adaptive immune system ( Pro-inflammatory Th1 cells generate cytokines including TNF- and IFN-, which are essential for combating intracellular infections

a - j , Whole-brain 3D mapping and quantification of cFOS responses to treatment single s.c

However, it is unclear exactly which isoform acts in cardiomyocytes and how it exerts its anti-ferroptosis effect, which requires further study

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