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In addition to its hyperglycaemic action, glucagon has been reported to activate lipolysis and inhibit lipogenesis in the liver

In contrast, when analyzing stroke outcomes, the effect was more pronounced with GLP-1 RAs, which provided the greatest contribution to the reduction of stroke events

PMID: 24651458

doi: 10.1111/andr.2018.6.issue-2 211 GualtieriRKalthurGBarbatoVLongobardiSDi RellaFAdigaSKet al

Weight reduction can improve IR, muscle energy balance, and muscle microcirculation by restoring glucose metabolism and oxidative phosphorylation and improving mitochondrial function

Doubling your dose will not speed up results